Clinical Notices

As a service to our members, prescribers, and pharmacy partners, RxAdvance is providing information regarding the latest news in drug therapy, including information about recently approved drugs, new generics, changes in drug therapy indications, and changes to clinical treatment guidelines. Additionally, updates to the National Drug Formulary are provided here. Keep a pulse on the latest drug industry news and more with the following clinical notices.

Affected Product(s)Notice TypeDate of Notice 
Gavreto® (pralsetinib)New Drug Approval09/04/2020View PDF
Onureg (azacitidine)Clinical Update09/01/2020View PDF
Kesimpta Pen (ofatumumab)Clinical Update08/20/2020View PDF
Cystadrops® (Cysteamine ophthalmic solution)Clinical Update08/19/2020View PDF
Tecfidera (dimethyl fumarate capsule)First Time Generic Approval08/17/2020View PDF
ENSPRYNG™ (satralizumab-mwge)New Drug Approval08/14/2020View PDF
VILTEPSO™ (Viltolarsen)New Drug Approval08/12/2020View PDF
MultipleFormulary Update08/11/2020View PDF
EVRYSDI™ (risdiplam)New Drug Approval08/07/2020View PDF
Dovato (dolutegravir and lamivudine) TabletsClinical Update08/06/2020View PDF
BLENREP (belantamab mafodotin-blmf)New Drug Approval08/05/2020View PDF
Spravato (esketamine) Nasal Spray
Clinical Update07/31/2020View PDF
Epidiolex (cannabidiol) Oral SolutionClinical Update07/31/2020View PDF
Monjuvi® (tafasitamab-cxix)New Drug Approval07/31/2020View PDF
Tecentriq (atezolizumab) Injection
Clinical Update07/30/2020View PDF
DEMSER® (metyrosine)First Time Generic Approval07/24/2020View PDF
TECARTUS™ (brexucabtagene autoleucel)New Drug Approval07/24/2020View PDF
Breztri Aerosphere™ (glycopyrrolate and formoterol fumarate)New Drug Approval07/23/2020View PDF
Narcan; Evzio (naloxone)Clinical Update07/23/2020View PDF
Qutenza (capsaicin) Transdermal PatchClinical Update07/17/2020View PDF
Jadenu® Sprinkle (deferasirox)First Time Generic Approval07/14/2020View PDF
Tremfya (guselkumab) InjectionClinical Update07/13/2020View PDF
UPNEEQ (oxymetazoline hydrochloride ophthalmic solution)New Drug Approval07/08/2020View PDF
Dysport (abobotulinumtoxinA) InjectionClinical Update07/08/2020View PDF
Botox (onabotulinumtoxinA) InjectionClinical Update07/08/2020View PDF
INQOVI®(decitabine and cedazuridine)New Drug Approval07/07/2020View PDF
Rukobia™ (fostemsavir)New Drug Approval07/02/2020View PDF
Tralement™ (trace elements injection 4)Clinical Update07/02/2020View PDF
RUKOBIA (fostemsavir)New Drug Approval07/02/2020View PDF
Bavencio (avelumab) InjectionClinical Update06/30/2020View PDF
Stelara (ustekinumab) InjectionClinical Update06/30/2020View PDF
Keytruda (pembrolizumab) InjectionClinical Update06/29/2020View PDF
Keytruda (pembrolizumab) for InjectionClinical Update06/29/2020View PDF
PHESGO™ (pertuzumab, trastuzumab, and hyaluronidase-zzxf)New Drug Approval06/29/2020View PDF
MYCAPSSA®(octreotide)Clinical Update06/26/2020View PDF
FINTEPLA® (fenfluramine)New Drug Approval06/25/2020View PDF
Keytruda (pembrolizumab) Injection
Clinical Update06/24/2020View PDF
Xpovio(Selinexor) TabletsClinical Update06/22/2020View PDF
XPOVIO® (selinexor)New Drug Approval06/22/2020View PDF
Tazveik™ (tazemetostat)New Drug Approval06/19/2020View PDF
Gimoti® (metoclopramide hydrochloride)Clinical Update06/19/2020View PDF
Tazverik (tazemetostat) Tablets Clinical Update06/18/2020View PDF
Dupixent (dipulumab) InjectionClinical Update06/18/2020View PDF
Crysvita (burosumab-twza) InjectionClinical Update06/18/2020View PDF
Keytruda (pembrolizumab) for InjectionClinical Update06/16/2020View PDF
Cosentyx (secukinumab) InjectionClinical Update06/16/2020View PDF
Ilaris (canakinumab) InjectionClinical Update06/16/2020View PDF
ZEPZELCA™ (lurbinectedin)New Drug Approval06/15/2020View PDF
LYUMJEV™ (insulin lispro)New Drug Approval06/15/2020View PDF
Gardasil 9 (human papillomavirus 9-valent vaccine, recombinant) InjectionClinical Update06/12/2020View PDF
TIVICAY PD (dolutegravir)Clinical Update06/12/2020View PDF
Tivicay® and Tivicay® PD (dolutegravir)Clinical Update06/12/2020View PDF
Semglee™ (insulin glargine injection)Clinical Update06/11/2020View PDF
UPLIZNA™ (inebilizumab-cdon)New Drug Approval06/11/2020View PDF
Opdivo (nivolumab) InjectionClinical Update06/10/2020View PDF
Dojolvi™ (triheptanoin)New Drug Approval06/06/2020View PDF
Recarbrio (imipenem, cilastatin, and relebactam) for InjectionClinical Update06/04/2020View PDF
Taltz (ixekizumab) InjectionClinical Update05/29/2020View PDF
Cyramza (ramucirumab) InjectionClinical Update05/29/2020View PDF
Tecentriq (atezolizumab) InjectionClinical Update05/29/2020View PDF
ZILXI™ (minocycline)New Drug Approval05/29/2020View PDF
Brilinta (ticagrelor) TabletsClinical Update05/28/2020View PDF
Sirturo (bedaquiline) Tablets Clinical Update05/27/2020View PDF
Dupixent (dupilumab) InjectionClinical Update05/26/2020View PDF
VESIcare (solifenacin succinate) TabletsClinical Update05/26/2020View PDF
MultipleFormulary & Clinical Updates05/25/2020View PDF
Alunbrig (brigatinib) TabletsClinical Update05/22/2020View PDF
KYNMOBI™ (apomorphine hydrochloride)New Drug Approval05/21/2020View PDF
Samsca® Tablets (tolvaptan tablets)First Time Generic Approval05/19/2020View PDF
Lynparza (olaparib) TabletsClinical Update05/19/2020View PDF
Ferriprox (deferiprone) Tablets and Oral SolutionClinical Update05/19/2020View PDF
Tecentriq (atezolizumab) InjectionClinical Update05/18/2020View PDF
Noxafil® Oral Suspension (posaconazole oral suspension)
First Time Generic Approval05/15/2020View PDF
Rubraca (rucaparib) TabletsClinical Update05/15/2020View PDF
Qinlock™ (ripretinib)New Drug Approval05/15/2020View PDF
Opdivo (nivolumab) InjectionClinical Update05/15/2020View PDF
Pomalyst (pomalidomide) CapsulesClinical Update05/14/2020View PDF
Nexium® 24HR DelayedRelease Tablets (esomeprazole magnesium
First Time Generic Approval05/14/2020View PDF
Taclonex® (calcipotriene and betamethasone dipropionate)First Time Generic Approval05/11/2020View PDF
Desonate® (desonide gel 0.05%)First Time Generic Approval05/11/2020View PDF
Lynparza (olaparib) TabletsClinical Update05/08/2020View PDF
Retevmo™ (selpercatinib)New Drug Approval05/08/2020View PDF
Tabrecta™ (capmatinib)New Drug Approval05/06/2020View PDF
Farxiga (dapagliflozin) TabletsClinical Update05/05/2020View PDF
Zejula (niraparib) CapsulesClinical Update04/29/2020View PDF
Jublia (efinaconazole) Topical SolutionClinical Update04/26/2020View PDF
Plaquenil (hydroxychloroquine; chloroquine)
Clinical Update04/24/2020View PDF
Adrenalin® (epinephrine Injection USP)First Time Generic Approval04/24/2020View PDF
Ongentys® (opicapone)New Drug Approval04/24/2020View PDF
Meningococcal (Groups A, C, Y, W)
Conjugate Vaccine (MenQuadfi®)
Clinical Update04/23/2020View PDF
Trodelvy™ (sacituzumab govitecan-hziy)New Drug Approval04/22/2020View PDF
Cloderm™ (clocortolone pivalate)First Time Generic Approval04/21/2020View PDF
Imbruvica (ibrutinib) Capsules and TabletsClinical Update04/21/2020View PDF
Pemazyre™ (pemigatinib)New Drug Approval04/17/2020View PDF
MultipleFormulary & Clinical Updates04/15/2020View PDF
Butrans® (buprenorphine transdermal system)First Time Generic Approval04/14/2020View PDF
Koselugo™ (selumetinib)New Drug Approval04/10/2020View PDF
Braftovi (encorafenib) CapsulesClinical Update04/08/2020View PDF
Reblozyl (luspatercept-aamt) for Injection Clinical Update04/03/2020View PDF
Tukysa™ (tucatinib)New Drug Approval04/01/2020View PDF
Imfinzi (durvalumab) InjectionClinical Update03/30/2020View PDF
Triferic (ferric pyrophosphate citrate)Clinical Update03/27/2020View PDF
Taltz (ixekizumab) InjectionClinical Update03/26/2020View PDF
Zeposia® (ozanimod)New Drug Approval03/25/2020View PDF
Eucrisa (crisaborole) Topical OintmentClinical Update03/23/2020View PDF
Nexium® 10 mg OS (esomeprazole magnesium delayed-release for oral suspension, 10 mg)First Time Generic Approval03/23/2020View PDF
Nexium® 20 mg, 40 mg OS (esomeprazole magnesium)First Time Generic Approval03/23/2020View PDF
Isturisa® (osilodrostat)New Drug Approval03/06/2020View PDF
Evomela™ (melphalan)
First Time Generic Approval03/06/2020View PDF
Singulair (montelukast)Clinical Update03/04/2020View PDF
Riomet® (metformin hydrochloride)First Time Generic Approval03/03/2020View PDF
Sarclisa® (isatuximab-irfc)New Drug Approval03/02/2020View PDF
Tepadina® (thiotepa injection)First Time Generic Approval03/04/2020View PDF
Migranal® (dihydroergotamine mesylate)First Time Generic Approval02/28/2020View PDF
Nurtec™ ODT (rimegepant)New Drug Approval02/27/2020View PDF
Barhesys® (amisulpride)New Drug Approval02/26/2020View PDF
Daraprim® (pyrimethamine)First Time Generic Approval02/26/2020View PDF
ProAir® HFA (albuterol sulfate inhalation aeroso)First Time Generic Approval02/24/2020View PDF
Vyepti™ (eptinezumab-jjmr)
New Drug Approval02/21/2020View PDF
Nexletol™ (bempedoic acid)New Drug Approval02/21/2020View PDF
Vimovo® (naproxen and esomeprazole magnesium tablets)First Time Generic Approval02/18/2020View PDF
TWIRLA® (levonorgestrel and ethinylestradiol)New Drug Approval02/14/2020View PDF
Belviq; Belviq XR (lorcaserin)Clinical Update02/13/2020View PDF
Proventil® HFA (albuterol sulfate inhalation aerosol 90 mcg, (base)/actuation)First Time Generic Approval02/08/2020View PDF
Hicon® (sodium Iodide I 131 Solution USP and Sodium Iodide I 131 Capsules USP)First Time Generic Approval02/02/2020View PDF
MultipleFormulary & Clinical Updates02/2/2020View PDF
Clozaril (clozapine)Clinical Update01/28/2020View PDF
BYNFEZIA™ (octreotide acetate)New Drug Approval01/28/2020View PDF
Zohydro® ER (hydrocodone bitartrate ER capsule)First Time Generic Approval01/21/2020View PDF
Tepezza™ (teprotumumab-trbw)New Drug Approval01/21/2020View PDF
Monoferric® (ferric derisomaltose)New Drug Approval01/16/2020View PDF
Ayvakit™ (avapritinib)New Drug Approval01/09/2020View PDF
Hemady™ (dexamethasone)Clinical Update10/03/2019View PDF
ORTIKOS® (budesonide)Clinical Update06/13/2019View PDF
Kuvan® (sapropterin dihydrochloride)First Time Generic Approval05/10/2019View PDF
Emtriva® (emtricitabine)First Time Generic Approval07/02/2018View PDF
MoviPrep (Peg-3550, sodium sulfate, NaCl, KCL,
sodium ascorbate and ascorbic acid)
First Time Generic Approval01/25/2012View PDF